Areas of interest span the basic sciences of chemistry, biochemistry and microbiology, through to pharmacology and clinical medicine, in the el te de canela es bueno para la diabetes of mycobacterial pathogenesis and TB drug discovery research. His primary research interests are C-type lectin receptors and their role in homeostasis and immunity, with a particular focus on antifungal immunity. His research interests revolve around investigating immune regulation and dysregulation in the context of HIV infection or exposure. He focuses on Immune ontogeny in HIV exposed infants, placental investigations and pre-term birth, and epithelial immunity in the foreskin.
Chair of the standing committee on Health, ASSAF. Her Research Unit is involved with clinical research, epidemiology and operational research, and is a treatment site for HIV infected adults and children. Her research interests include HIV vaccine research, microbicide research and other biomedical and behavioural interventions, and she is an investigator in testing two HIV vaccine regimens in late stage clinical development. Her TB research includes examining new agents to prevent TB, TB prophylaxis and TB vaccine evaluation. Specialist in Internal Medicine, Infectious Diseases, Tropical Medicine.
Full Professor and Chair of Tropical Medicine and Travel Medicine and Head, Center of Tropical Medicine and Travel Medicine, Amsterdam Medical Centre, University of Amsterdam in the Netherlands. He has been an author on over 150 manuscripts in the field of infectious diseases and has an extensive track record in infectious diseases research and practice covering clinical, laboratory and epidemiological aspects. Wellcome Trust senior Fellow, department of infection and immunity, University College London, UK. He is an HIV and TB immunologist focused on studying the immune response to these pathogens in affected tissues, and how this relates to what can be observed from the blood. The research goal is to improve understanding of the immunopathology of TB and HIV, using this information to aid in developing novel therapeutic approaches and diagnostic biomarkers. MD, PhD, Professor and Vice Chair for Research, Department of Medicine, Director OHSU Center for Global Child Health Research, Department of Pediatrics. T cells, with a focus on both those antigens that are recognised, and the means by which they are presented.
His work has a strong translational component, asking if both classically and non-classically restricted T cells are associated with infection with M. MD, Professor, and Vice Chair for Research, Division Head Infectious Disease, Wayne L. Tracy Professor of Infectious Disease, Department of Pediatrics, Assistant Director, OHSU Center for Global Child Health Research. T cells in host defense to TB.
The translational significance of this research is centred on informing the development of novel vaccines and diagnostics for childhood TB. South African Research Chair in Viral Host Dynamics, Faculty of Health Sciences, University of Witwatersrand and National Institute for Communicable Diseases. Her current research focuses on HIV broadly neutralising antibodies and their interplay with the evolving virus. Recent studies published in PloS Pathogens, Nature and Nature Medicine have highlighted the role of viral escape in creating new epitopes and immunotypes, thereby driving the development of neutralisation breadth, with implications for HIV vaccine design. Research interest in tuberculosis and in developing and testing point of care diagnostics suitable for the developing world. Assistant Professor of Medicine at Johns Hopkins University. Honorary Associate Professor, Department of Medicine, University of Cape Town.
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